Abstract Background New digital PET scanners with improved time of flight timing and extended axial field of view such as the Siemens Biograph Vision have come on the market and are expected to replace current generation photomultiplier tube PMT -based systems such as the Siemens Biograph mCT. These replacements warrant a direct comparison between the systems, so that a smooth transition in clinical practice and research is guaranteed, especially when quantitative values are used for dosimetry-based treatment guidance. The new generation digital PET scanners offer increased sensitivity. This could particularly benefit 90Y imaging, which tends to be very noisy owing to the small positron branching ratio and high random fraction of 90Y. This study aims to determine the ideal reconstruction settings for the digital Vision for quantitative 90Y imaging and to evaluate the image quality and quantification of the digital Vision in comparison with its predecessor, the PMT-based mCT, for 90Y imaging in radioembolisation procedures.

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This means the system combines two high quality modalities in one machine, whereas with conventional PET-CT systems the CT component has limitations for complicated CT examinations. To increase patient comfort, we have now integrated both components in a very small system, so that the scanner has a tunnel length of only one metre. This means that examinations with the Biograph mCT can be carried out in just five to six minutes, whereas conventional machines still take about half an hour.

With its adaptive dose shield, a scanning area of up to two metres and a maximum time resolution of up to milliseconds — with slices per rotation — the CT scanner ensures pin-sharp and clear images. This makes it suitable for routine diagnostics as well as complex examinations in cardiology and oncology. These are different medical disciplines. The mCT constitutes the interface between radiology and nuclear medicine.

Will these two disciplines be forced into increased cooperation due to this technical development? It means that nuclear medicine specialists and radiologists jointly establish the diagnosis. A specialist in nuclear medicine typically cannot evaluate and diagnose the results of a CT examination, and a radiologist cannot evaluate PET results, so we are supporting closer cooperation with our mCT.

But this has a significant bias towards radiology. Some hospitals in Germany have nuclear medicine departments and professorships.

To use the new mCT effectively, radiology and nuclear medicine will now have to work together in one department. For example, this type of CT can actually be used for organ perfusion. If you then superimpose the result with that of a PET examination — and this is where nuclear medicine comes into play — you gain a third type of measurement, at no extra expense, which can be relevant for fast and precise diagnosis.

So they are only driving your luxury limousine in first gear? ML: Only in first gear, and to pop to the shops, so to speak. And this was why Siemens focused on how to motivate users to make full use of the potentials of a CT examination. The solution: an enhanced CT that can also be used to carry out CT angiography. The mCT can give a surgeon a complete image of the lungs, for example. This clearly shows where the bronchial tubes and tumours are.

It can even show blood vessels — and all this in an integrated examination for which the Biograph Molecular CT only requires a fraction of the time that currently used machines take to do it.


Manufacturer Specifications - Biograph mCT, Siemens

This unique combination of technologies results in improved image quality reduced scan times and increased patient comfort. First introduced at EANM in , the Biograph mCT has achieved widespread global adoption due to its game-changing features and benefits. A uniform 2mm image resolution throughout the entire field of view can significantly improve image quality and offer clinicians increased confidence in diagnosis. The ability for five-minute, whole-body PET scanning, combined with a large bore and short tunnel, offers a more flexible solution for demanding workflows, as well as a more comfortable environment for the patient. Among the first to work with the new system is Dr. PET and CT scans alike can be performed by one team of operators using only one schedule and.


Siemens Biograph mCT PET/CT


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