Arashikazahn Ethylcellulose and hypromellose act as release modifiers for this water-soluble drug. We take care to continuously monitor and evaluate our capabilities to identify new challenges and avenues for improvement. The core layer contained theophylline while the outer layers were composed of polymers and excipients in order to delay the interaction of the core layer with water, thereby delaying and controlling the drug release. A study that was conducted by Fassihi and co-workers investigated zero-order release kinetics from a self-correcting floatable asymmetric configuration drug delivery system. Namdeo expressed that multilayered tablets have demonstrated promise, possessing various benefits, namely the ability to prevent interactions between drugs and excipients; and yeomatrix providing an array of release profiles in one delivery system of either the same or different drugs, treatment for conditions that require a regimen of more than one drug, immediate drug release using a disintegrating monolithic matrix in order to achieve an initial peak in plasma drug level, delayed drug release using an eroding monolithic matrix which may deliver another active drug to a different part of the gastrointestinal tract, providing controlled drug release instituting a swellable monolithic matrix and better control and regulation of release profiles by retarding initial burst release and achieving zero-order kinetics [ 64 ].

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Fera The relatively low dosage of this drug facilitates the rather complex dosage form design. Systems geomarix as multilayered tablets and other geometrically altered devices have been created to perform this function. Multilayered Floatable Drug Delivery Systems A study that was conducted by Fassihi and co-workers investigated zero-order release kinetics from a self-correcting floatable asymmetric configuration drug delivery system. The tablet demonstrated success in delivering nifedipine at a relatively constant rate for 24 hours [ 94 ]. Comparative evaluation of various structures in polymer controlled drug delivery systems and the effect of their morphology and characteristics on drug release.


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